• imageCo-occurring mental health
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  • imageHospital inpatient
  • imageInterim care
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Craig J. McClain, M.D., Professor, Departments of Medicine, and Pharmacology and Toxiology

Craig J. Mcclain, M.D., Dr. McClain is a Professor of Medicine and Professor of Pharmacology and Toxicology at the University of Louisville, where he also holds several research and administrative leadership positions. As a clinician and scientist, Dr. McClain has made many contributions to the alcohol research field. In an early study, he described the harmful interactions in the liver between alcohol and acetaminophen. In another landmark study, he described dysregulated cytokines in alcoholic hepatitis. Over time, Dr. McClain’s work has increasingly focused on translational and interventional studies, including a seminal clinical study demonstrating the beneficial effects of nutritional supplementation in alcoholic hepatitis patients. He has studied extensively in his lab the interactions of the gut and liver in alcoholic liver disease generally and on the role nutrition plays in alcoholic liver disease. He has received continuous federal funding, including grants from NIH and the Department of Defense, for nearly 40 years.

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